CBG vs CBD for Anxiety

September 9, 2025
cbg vs cbd for anxiety

Anxiety can creep in out of nowhere and quickly derail whatever it is you’re doing. It gets in the way of work, relationships, and, of course, your own peace. Whether it’s triggered by something or just constantly lurking in the back of your mind, it can take a physical and mental toll.

The good news is there are plenty of ways to manage feelings of anxiousness. Mother Nature has provided one of the best remedies in cannabis. But which specific cannabinoids are most effective in comparing CBG vs CBD for anxiety? You’ve come to the right place.

You could make the case for either of these in managing anxious thoughts. CBD calms the mind and may modulate serotonin activity, assisting with situational stress or chronic worry. CBG plays a role by working with GABA and the endocannabinoid system (ECS) receptors directly.

Even microdosing THC for anxiety can have a powerful effect on how anxious you feel. That’s why we don’t believe in choosing between THC vs CBD vs CBG for anxiety. We think the best results come from combining these - and that’s the approach we’ve taken at Mr. Moxey’s.

From our CBD and THC mints to our THC and CBD shots and even our microdose gummies, we pair these cannabinoids with herbal allies (for mints and shots) like lemon, ginger root, agave, chamomile, and lemongrass. Get fast, lasting relief at Mr. Moxey’s today.

“I think these work super well, I feel very relaxed and nice to use in the evening.” - Hope

“I have used your Relief Mints for a few years now. I have IBS and a generally anxious stomach. These calm the symptoms immediately!!! Thank you!!!” - Anne

“I usually take the mints but tried this liquid shot and I felt relief instantly. It's so helpful with my Crohn's. The way this settles my stomach is incredible. I think this works better than any medication my doctor has given.” - Jen

Key Takeaways on Using CBG vs CBD for Anxiety:

  • Both CBG and CBD can help with anxiety, though they work through different mechanisms.
  • CBD doesn’t interact directly with the body’s endocannabinoid system. It regulates serotonin levels indirectly.
  • CBG interacts directly with both GABA and CB1 & CB2 receptors to evoke a sense of calm.
  • Together, they bring a more comprehensive support system to ease tension and calm a racing mind.
  • Mr. Moxey’s mints and shots bring these cannabinoids together (with THC) and proven herbal allies to help you get back to feeling like yourself. 

How Does CBD Help With Anxious Feelings?

This is perhaps the most well-known cannabinoid in the world, second only to maybe THC. It’s non-intoxicating, well-tolerated by most people, and has become a go-to option for those looking to ease discomfort or restlessness without altering their state of mind.

But what does CBD do when we talk about anxiety specifically? First, know that it doesn’t bind directly to the receptors in your body’s endocannabinoid system (ECS). Instead, it takes a more indirect approach.

One study looked at its role in influencing serotonin activity. CBD may interact with 5-HT1A receptors, which are closely linked to mood, stress, and social behavior.

That doesn’t mean CBD is a one-for-one replacement for pharmaceutical antidepressants or anti-anxiety drugs. But it does seem to support a sense of emotional balance by helping your body respond to stress in a healthier manner.

CBD can also support a calmer mental state by influencing the reuptake and availability of certain neurotransmitters. This may help extend the effects of naturally occurring compounds involved in managing fear responses so you’re not constantly “on edge.”

The appeal of CBD is that it does all this without flattening your energy or mental sharpness. You can take it morning, day, or night without any sense of sedation. 

Whether you’re trying to start out on the right foot, preparing for a stressful meeting after lunch, or winding down after a long, hectic day - CBD might be just what you need. But it’s just one piece of the puzzle. Let’s introduce the other half of our comparison of CBG vs CBD for anxiety.

How Does CBG Help With Anxious Feelings?

You probably haven’t heard nearly as much about CBG, but this minor cannabinoid is pretty special. It’s actually called the “mother” of cannabinoids because many other cannabinoids, including CBD and THC, are synthesized from it early in the plant’s development.

But CBG itself is a fully formed cannabinoid with its own unique effects, and it deserves more respect - especially for how it supports a calm, clear mindset for people struggling with feelings of anxiousness.

CBG appears to interact more directly with both CB1 and CB2 receptors in the ECS. These receptors help manage emotional regulation, nervous system activity, and inflammatory responses. In other words, CBG might have a more profound effect without being intoxicating or overstimulating.

One of the more interesting things about CBG is its relationship with GABA, a neurotransmitter known for its calming effects. We still have a lot to learn about this connection, but it looks like CBG helps boost GABA uptake. This means it may help you feel more relaxed. It could be your saving grace if you always feel tense or jittery, but don’t want to feel “sleepy.”

CBG is also known for supporting sharper focus and mental clarity. We know what you’re thinking…that sounds a bit contradictory to its calming effects. But it actually makes CBG a perfect match for people whose anxiety shows up as scattered thoughts or racing mental loops.

Most people don’t use CBG on its own. It usually does its best work when paired with CBD or even small amounts of THC in balanced formulations. That’s what makes our mints and shots so powerful - they bring you ALL the support you need to find your zen.

More on that in a few minutes. We want to compare CBG vs CBD for anxiety side by side first.

CBG vs CBD for Anxiety: Which is More Effective?

It’s hard to say one is inherently “better” than the other in looking at CBD vs CBG for anxiety. There’s a bit of overlap, and they work best for different types of anxious triggers or feelings. As we’ve said throughout, you’ll probably feel the most relief from a combination of the two.  

Different Paths to a Similar Goal

CBD and CBG both support a sense of calm, albeit through very distinct routes. Think of them as complementary tools rather than direct competitors.

CBD tends to soothe the nervous system by working with serotonin and other chemical messengers. It helps soften the emotional edge that often comes with stress. CBG, on the other hand, is more focused and gently energizing. Think clear-headed calm; mellow concentration.

When CBD Might Be the Better Choice

CBD tends to work best for people who experience anxiety in a more physical or emotional way. They struggle with a tight chest, nervousness in social settings, difficulty falling asleep, or persistent low-level tension. It’s also a good fit if you’re winding down in the evening, specifically.

When CBG Might Offer More Targeted Support

CBG might be the smarter choice if your anxiety shows up as racing thoughts, overstimulation, or trouble concentrating. Does it feel like your mind is scattered or you're feeling mentally tense even when your body seems calm? CBG can probably bring the clear sense of relief you crave.

We find CBG to be the smarter option during the daytime in particular. It’s a great choice before work presentations, during long stretches of focus, or when you want to stay calm without losing alertness. It’s “anchoring,” not sedating. 

How They Can Work Better Together in Low Doses

It’s not a matter of choosing between CBG vs CBD for anxiety, but rather, understanding how they work in synergy to bring you back into balance. Think about it like this - CBD helps regulate mood and ease physical tension, while CBG supports mental clarity and emotional regulation.

Together, they can create a more complete response to stress. Less foggy than CBD alone, less sharp than CBG on its own. It’s the sweet spot for a lot of people struggling with anxious feelings.

We have a more detailed guide comparing CBG vs CBD vs CBN if you want to learn more. But one thing we’re asked all the time, aside from which is better between CBG vs CBD for anxiety, is the role THC plays. Let’s take a look.

What About THC for Anxiety?

THC’s role in anxiety is a bit more nuanced than CBD or CBG because too much can actually have the opposite intended effect in a lot of individuals. But, it can help people relax, release tension, and shift their mental state at lower doses.

This sensitivity to dosage is part of what makes THC both promising and tricky when it comes to supporting anxious feelings. The key isn’t avoiding it entirely, but learning how to use it intentionally, in measured amounts, and alongside other cannabinoids that round out its effects.

For instance, CBD has a modulating effect on THC. It can sharpen out the harsh edges THC might have on its own, lessening that stimulation and paranoia you might have experienced with pure THC products in the past.

So, it’s clear that you shouldn’t focus on isolating CBD vs CBG for anxiety, or even THC for that matter. You need to bring together the benefits of CBD and THC together with CBG. We make it easy and enjoyable at Mr. Moxey’s.

Get All Three Cannabinoids in One Formula at Mr. Moxey’s

We believe wellness should feel intuitive, empowering, and personal. Our philosophy is rooted in microdosing done right, giving you total control over your experience, while helping plant-based cannabinoids work in gentle, effective harmony with your body.

Our anxiety mints are a thoughtfully balanced 1:1:1 blend of CBD, THC, and CBG (2.5mg of each per mint). You get full-spectrum support for anxious thoughts, minor physical discomfort, and that general feeling of being off. You also get calming chamomile and lemongrass.

Meanwhile, our anxiety shot takes things up a notch and offers faster effects. You get the same 1:1:1 cannabinoid profile - this time with 5mg each of CBD, THC, and CBG per shot. You also get a slightly different herbal blend: organic ginger, lemon, and agave.

We also have stress mints that give you 5mg of CBD and 2.5mg of THC for a more focused blend, combined with linden blossom and hop flowers for a comforting, cozy feeling as tension melts away.  

Now, if you just want cannabis support without any herbal allies, our anxiety gummies or stress gummies are worth exploring. They bring you 5mg each of CBD, THC, and CBG, or 10mg of CBD and 5mg of THC, respectively. 

No matter what you go with from Mr. Moxey’s, you can rest assured you’re getting 3rd-party lab-tested cannabis products that comply with the 2018 Farm Bill - shipped legally and discreetly to your doorstep. Relief is just a few clicks away. Treat yourself today!

Closing Thoughts on CBD vs CBG for Anxiety

Maybe your anxiety is caused by work. Perhaps it’s relationships. It could be nothing at all, but something just feels off. Whatever the case, cannabis can help - and you know what your next steps should be as we wrap up our guide to using CBD vs CBG for anxiety.

We hope this comparison of CBG vs CBD for anxiety has left you with total clarity on the role each plays in helping you find your inner zen. The key takeaway? Using the two together, along with THC and other proven herbal allies, is your best route towards relief.

Our anxiety mints and shots bring you fast, lasting clarity and calm. Join thousands who rely on our hemp-derived cannabis products to feel more like themselves on a day-to-day basis.

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